Stroke Research Today is a free monthly online journal that collates and summarizes the latest research about Stroke, including details on treatment, recovery, rehabilitation, signs, symptoms.

Mortality of stroke patients treated with thrombolysis: analysis of nationwide inpatient sample.

Dubinsky R, Lai SM

University of Kansas Medical Center, Department of Neurology, Kansas City, KS 66160, USA. rdubinsky@safetyresearch.com

The authors performed a retrospective cohort comparison using the Nationwide Inpatient Sample for 1999 through 2002 of acute ischemic stroke admissions. Mortality was compared based on the use of thrombolysis. Hospital mortality was significantly greater for the thrombolysis cohort (10.1% vs 5.8%) as was the rate of secondary intracranial hemorrhage (4.2% vs 0.4%). US community experience in the use of thrombolysis has higher rates of complications and mortality than in controlled clinical trials.

Published 13 June 2006 in Neurology, 66(11): 1742-4.
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