Stroke Research Today is a free monthly online journal that collates and summarizes the latest research about Stroke, including details on treatment, recovery, rehabilitation, signs, symptoms.

Statin enhancement of collateralization in acute stroke.

Ovbiagele B, Saver JL, Starkman S, Kim D, Ali LK, Jahan R, Duckwiler GR, Viñuela F, Pineda S, Liebeskind DS

Department of Neurology, UCLA Medical Center, Los Angeles, CA 90095, USA. ovibes@mednet.ucla.edu

Collateral circulation influences cerebral infarction occurrence and size. Statins may improve ischemic stroke outcomes. We evaluated the relationship between prestroke statin use and pretreatment angiographic collateral grade among acute ischemic stroke patients presenting with occlusion of a major cerebral artery. After adjusting for covariates, the statin-treated group had significantly higher collateral scores than non-statin users, suggesting an association between statin use and better collateralization during acute stroke.

Published 12 June 2007 in Neurology, 68(24): 2129-31.
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